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  6. Denestra SAMe 200 mg (60 Tablets)

  • SAME200MG60SAME200MG60
  • SAME200MG60SAME200MG60
  • SAME200MG60SAME200MG60
  • SAME200MG60SAME200MG60
  • SAME200MG60SAME200MG60
  • SAME200MG60SAME200MG60
  • SAME200MG60SAME200MG60
  • SAME200MG60SAME200MG60
  • SAME200MG60SAME200MG60

Denestra SAMe 200 mg (60 Tablets)

Item: SAME200MG60
39.59
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Description

Denestra SAMe is a dietary supplement that contains S-Adenosylmethionine (SAMe), a naturally occurring compound found in the body. SAMe plays a vital role in various biochemical processes, including the production of neurotransmitters and the maintenance of cell membranes.

Key Benefits:

  1. Liver Health: SAMe is known for its positive effects on liver health. It supports the production of glutathione, a powerful antioxidant that helps protect liver cells from damage caused by toxins, medications, and oxidative stress.
  2. Mood and Emotional Well-being: SAMe is involved in the synthesis of neurotransmitters such as serotonin, dopamine, and norepinephrine, which are crucial for regulating mood and emotions. Supplementing with SAMe may help improve mood, reduce anxiety, and alleviate symptoms of depression.
  3. Joint Health: SAMe has anti-inflammatory properties that can help reduce joint pain and inflammation. It is often used as a complementary therapy for conditions like osteoarthritis, where it can support joint mobility and promote overall joint health.
  4. Cognitive Function: SAMe is believed to have neuroprotective properties and may help support cognitive function and memory. It is being investigated for its potential benefits in conditions such as Alzheimer's disease and age-related cognitive decline.
  5. Energy and Vitality: SAMe is involved in the production of adenosine triphosphate (ATP), which is the body's primary energy source. By supporting ATP production, SAMe may help improve energy levels, promote vitality, and reduce fatigue.

It's important to note that individual results may vary, and it's always recommended to consult with a healthcare professional before starting any new dietary supplement.

Specifications:

  • Pet Life Stage: Adult, Senior
  • Food Form: Supplement
  • Breed Size: Small Breeds, Medium Breeds, Large Breeds, All Breeds, Giant Breeds, Extra Small Breeds
  • Product Form: Tablet
  • UPC: 814087006073
Uses

Denestra with SAMe supports liver metabolic activity and proper liver function for dogs and cats. SAMe, or S-Adenosyl-Methionine, is a naturally occurring substance found in all living beings. SAMe in its biological form contributes to better pet health through a number of chemical processes: transmethylation, transsulfuration, and aminopropylation.

Benefits

These processes can affect liver and joint health in animals. Through the process of transsulfuration, natural SAMe is converted into a compound called glutathione, a potent antioxidant and liver detoxification tool. It supports normal detoxification and cleansing of the liver from impurities, which in turn may help the body from exposure to heavy metal or environmental toxins.

Additional Benefits

Denestra with naturally occurring SAMe has added benefits for pet joint health as well. During the aminopropyl ation process, methylthioadenosine (MTA) is produced. MTA helps support cartilage matrix production in the joints, and may help maintain the effectiveness of proteoglycans, molecules that are critical for the lubrication of joints.

Ingredients

Ingredients:

S-Adenosyl-L-methionine disulfate p-toluensulfonate, Microcrystalline cellulose, Mannitol, Carboxymethylstarch sodium salt, Colloidal silica anhydrous, Glycerol behenate, Magnesium stearate.

Coating Ingredients:

Methacrylic acid copolymer, Glycerol palmitostearate, Medium chain triglycerides, Titanium dioxide, Colloidal silica anhydrous, Talc, Triethyl citrate, Yellow iron oxide (III).

Useful Information

Administration
Animal Weight Daily
Less than 15 lbs. 1 Tablet
16-35 lbs. 2 Tablets

Denestra® should be administrated on an empty stomach, one hour before or two hours after a meal (overnight fast is preferred). Do not cut or crush tablets. May be disguised in treats for easier administration. Dosage may be increased or decreased at any time at the recommendation of your Veterinarian.

CAUTIONS:

If animal's condition worsens or does not improve, stop product administration and consult your Veterinarian. In case of accidental overdose, contact a health professional immediately.

WARNINGS:

For use in animals only.

STORAGE:

Store in a cool dry place. Keep out of reach of children and pets. Keep tablets in their original blister pack until used. Tablets are sensitive to moisture and extreme heat.

Customer Reviews

Review Summary
4.6
19 Reviews
5
74% (14)
4
21% (4)
3
0% (0)
2
0% (0)
1
5% (1)
94.74% Recommend this product (18 of 19 responses)
By William S.
good product
January 26, 2024
seems to be excellent quality based on our dogs blood tests
* This product review was collected by the manufacturer.
By PC
Cheaper option than other brands.
December 15, 2022
I have a senior pitty mix that has liver problems and was put on Danimerin, which is very EXPENSIVE. I did my research trying to find something as effective but more affordable and this is it. It has kept her liver levels normal or close to.
* This product review was collected by the manufacturer.
By Reynel
Buenísimo
September 27, 2022
Buenísimo
* This product review was collected by the manufacturer.
By Verna B.
I would recommend!
September 16, 2022
Helped my dog with immune system.
* This product review was collected by the manufacturer.
By J M.
Senior Fur Babies SamE joint, liver, and Cognitive Function
August 13, 2022
We have used this for the second dog we have had now. She is now 14 and very active for her age. It has been very beneficial for both of these dogs - one made it to 16 and now the second.
* This product review was collected by the manufacturer.
By William B.
It works an works well.
September 23, 2021
No dislikes
* This product review was collected by the manufacturer.
By S B.
Good price!
September 5, 2021
I was very pleased at the price. It was more reasonable than I had previously found. The product arrived quickly.
* This product review was collected by the manufacturer.
By Linda
NL
Denestra
November 24, 2020
These pills are doing wonders for my Shih tzu/pug who is suffering from Cushings Disease and IMHA. The only fault is that the pills are so large.

Merchant Response:Hi Linda, love to hear your review. I hope your Shih tzu/pug feels better.
By lev s.
damaged goods
May 6, 2020
Ripped box 40 out of 60 pills are cut open , ridiculous !!!
* This product review was collected by the manufacturer.
By Craig D.
Four Stars
July 1, 2018
fast and nice
* This product review was collected by the manufacturer.
By Adam H.
Five Stars
December 19, 2017
This product is great. Helped my dog tremendously.
* This product review was collected by the manufacturer.
By Cierra
Best alternative to prescription supplements!
December 14, 2017
My dog was recommended to be on a prescription liver supplement for the rest of her life after chronic high liver enzymes. I purchased these after using the extremely expensive prescription brand for 2 months. These have the same dosage of SAMe as the prescription brand. The combination of modifying my dogs diet and using this supplement, along with following veterinarian recommendations have decreased her liver enzymes and brought her back within normal limits. The blister pack is more reliable than purchasing in a bottle, as this supplement is sensitive to moisture. I'm not going to lie, the pill stinks! But my dog is not picky and eats this on an empty stomach with a tiny bit of peanut butter. I will continue to keep her on this supplement! Thank you for providing a more affordable alternative!
* This product review was collected by the manufacturer.
By Gwennie
Antioch, Ca
Denestra
October 27, 2016
I am happy with it. It is easy to give in a Pill Pocket and it seems to be helping his digestive issues.
By DM H.
this was the best price with free shipping at the time I needed ...
October 21, 2016
My senior schnauzer has taken this daily for several years, this was the best price with free shipping at the time I needed to reorder.
* This product review was collected by the manufacturer.
By cATHY
Very Happy!!!!
July 23, 2016
Very happy with the denestra cheaper than zentonil and does wonders to my Yoko .. Thank's
By nicky
new zealand
Great product
June 19, 2014
Have used it on 2 of my elderly dogs with liver disease now and for both of them it dramatically reduced their liver enzyme counts and maintained them at the lower levels. I use it in conjunction with human milk thistle (100mg) tablets as Denestra doesn't contain silymarin which is also a must have in my book. I import this produce into New Zealand for my dogs and it still works out at a fraction of the cost!!
By APS
Review for Denestra SAMe 200 mg (60 Tablets)
February 3, 2012
This is working. I'll find out today for sure when my Penny gets her levels checked again, but it seems to be doing a great job! She feels a lot better & is playing around more.
By Maggie
HILTON HEAD ISLAND, SC
DENESTRA
November 14, 2011
I AM SO HAPPY THAT ONE OF YOUR REPS SUGGESTED I TRY DENESTRA FOR MY SHIH TZU'S LIVER PROBLEM. IT IS A LOT CHEAPER THEN THE ZENTONIL 200 THAT I WAS ORDERING FOR HIM.THANKS TO THE REP WHO SUGGEST THAT I TRY DENESTRA ALSO CALLED SAME. MY SONNY HAD A TUMOR ON THE GLAND NEXT TO THE KIDNEY THE SIZE OF A GOLF BALL AND IT WAS PRESSING ON A MAIN BLOOD VESSEL, HIS SURGERY WAS 6/9/2011 AND HE IS DOING GREAT. WE SWITCHED T0 DENESTRA ON THE ORDER FOR MAY 16,2011. WE KNEW HE HAD A LIVER PROBLEM AND ONE VET THOUGHT HE MIGHT HAVE CUSHING DISEASE BUT DURING ALL THE TESTS FOR SURGERY WE FOUND OUT HE DOES NOT HAVE CUSHING DISEASE BUT WE ARE STILL GIVING HIM THE DENESTRA AND IT IS BETTER FOR MY POCKET BOOK!

MAGGIE
By Shelli
A Miracle Supplement
March 30, 2009
Our little dog had meningitis as a result of heartworm. He has to be on prednisone for probably the rest of his life. I worried about his liver and doctors couldn't tell me what I should give Jake for liver support. I went on-line to Entirelypets.com and looked under "liver support". With the advice of a customer service rep., I purchased Denestra and Marin. Within a few days after dosing Jake, he began feeling and acting like his young self again. He hasn't had any of the recurring symptoms since he has been taking the 2 supplements. I totally recommend them. It is absolutely a miracle.

Questions and Answers

1 Question & 1 Answer
Carol
from Orland, CA. asked:
March 29, 2017
how large is the tablet? It is difficult to disguise any meds for my dog. Thank you.
1 Answer
The tablet is about an inch long.
Submitted by: Customer Service on April 20, 2017

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