Zymox Plus Otic Advanced Formula w/ Hydrocortisone 1.0% (1.25 oz)
Item: IMW039971
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Description
ZYMOX® PLUS Advanced Otic Enzymatic Solution with 1% Hydrocortisone offers an enhanced approach to managing persistent or recurring ear irritations in pets. This advanced formula combines the patented LP3 Enzyme System with four additional biofilm-reducing enzymes: mutanase, dextranase, cellulase, and beta-glucanase. These enzymes target and break down the complex biofilms that contribute to antibiotic resistance and chronic infections. The addition of 1% Hydrocortisone provides significant relief from itching and discomfort caused by inflammation, dermatitis, and other minor skin irritations.
Uses:
- Effective against resistant otitis and infections from bacteria, fungi, and yeast.
- Ideal for pets with recurring ear problems linked to biofilms.
- Provides relief from itching and inflammation in the ears.
- Promotes overall ear health and is suitable for pets who swim or live in moist environments.
- Provides quick relief from ear infections, including symptoms of swimmer’s ear.
- Actively disrupts biofilms, enhancing the effectiveness against stubborn infections.
- Offers a soothing, non-stinging experience, ideal for sensitive pets.
- Contains an advanced enzyme system plus biofilm-reducing complex for superior effectiveness.
- Is a 3-day treatment vs 5-day treatment.
- Enhanced with 1.0% Hydrocortisone for additional itch and pain relief.
- Non-toxic and non-irritating, safe for use in dogs and cats.
- No pre-cleaning required, enabling easy, once daily application.
- Free from antibiotics, reducing the risk of adverse reactions and suitable for long-term use.
- Recommended by veterinarians for its efficacy and gentle formulation.
This product is proudly made in the USA, ensuring high-quality standards and reliable performance in pet ear care.
Ingredients
Benzyl Alcohol, Beta-Glucanase, Cellulase, Dextranase, Dextrose, D-Mannose, Glucose Oxidase, Glycerin, Hydroxypropyl Cellulose, Lactoferrin, Lactoperoxidase, Lysozyme, Mutanase, Potassium Iodide, Propylene Glycol, Purified Water, Hydrocortisone
Useful Information
Directions for Use:
If condition persists or worsens, consult your veterinarian.
Keep out of reach of children. Store at room temperature.
- Shake the bottle well before use.
- Apply liberally to the uncleaned ear canal.
- Gently massage the base of the ear to help the solution penetrate deeply.
- Wipe to remove excess solution and debris from the outer ear.
- Allow your pet to shake their head to assist in removing any remaining excess.
- Apply once daily for 7 days, or as directed by your veterinarian.
If condition persists or worsens, consult your veterinarian.
Keep out of reach of children. Store at room temperature.
| Features and benefits: |  HC FREE |  1.0% HC |  PLUS |
| DVM or pet owner seeking antibiotic alternative | X | X | X |
| Noage restrictions of the pet | X | X | X |
| Non species specific | X | X | X |
| Can be used in conjunction with oral meds | X | X | X |
| No side effects | X | X | X |
| Easy, 1x daily administration- squirt, rub, done | X | X | X |
| No cleaning before or during use | X | X | X |
Indications: | |||
| Pet is allergy-prone | X | X | |
| Plays in water | X | X | |
| Lives in humid enviroment | X | X | |
| Ocasional otitis | X | ||
| Unknown cause/no culture | X | X | |
| Exotics or rabbits | X | ||
| Pregnant or lactating females | X | ||
| Maintenance and prevention | X | X | |
Inflammation is apparent with: | |||
| Bacteria | X | X | |
| Fungal/yeast | X | X | |
| Polymicrobail | X | X | |
Presistant, unresolved otitis or recurring infections from complex biofilm forming microbes: | |||
| Bresistant Pseudomonas | X | ||
| Resistant Staph | X | ||
Customer Reviews
Review Summary
4.9
39 Reviews
5
95% (37)
4
3% (1)
3
3% (1)
2
0% (0)
1
0% (0)
100% Recommend this product (39 of 39 responses)
By JASPER
Indiana
ZYMOX PLUS
July 24, 2024
THIS IS THE ONLY PRODUCT IN THIS LINE OF ZYMOX THAT I USE IT WILL KNOCK OUT EAR PROBLEMS IN 7 DAY OF TREATMENT. IT IS THE BEST !!!! I LOVE MY FUR BABY !!
Pros
- THE BEST , THIS TAKES CARE OF MY FUR BABY . AND I CAN FEEL LIKE A GREAT MOM !!
Cons
- NONE
By Marie
New Hampshire
Vet Recommended
September 30, 2020
My dog seems to get chronic ear irritations. He will shake his head many times / day, and though there was no "infection", there was a small build-up, so our Vet recommended this product. We use it for 7 days and it seems to alleviate the problem.
Cons
- Very Pricey
By Jack
Zymox plus
July 12, 2017
This is the only product I have ever found that has actually worked. My cat had chronic ear problems for most of his adult life and this has given him some relief in that last year that I have been using it.
By Bower
Works better than the Vet
May 21, 2017
I spent a lot of money going to the Vet with no resolve. My dog's ears are great after using this product.
By Big D.
Best I've Found
May 3, 2017
I was a little skeptical at first but started using it as directed and such a GREAT and IMMEDIATE improvement! We tried everything from vet pills/drops to otc treatments. Wicked happy I got this product! I feel you won't be disappointed!
By Timie
Katy, Texas
Best so far
December 29, 2016
I have tried everything to get rid of the black junk in my dogs ear. This is the only thing that comes close. It does not get rid of it completely but almost.
By Susan
Webster, NY
The ONLY Thing That Works!
October 21, 2016
Zymox Plus has been the salvation for our poor dog's chronic ear issues. We went through the "vet route" -- antibiotics (several rounds), special ear wash, and prescription ear drops (one of which caused our dog to lose her hearing for 4 months). Nothing beats Zymox Plus. If you are discouraged with the lack of results and GIGANTIC vet bills from prescription treatments of chronic ear issues, please give Zymox Plus a try. You will NOT be disappointed!
By LuvShepherds
Webster, NY
AMAZING PRODUCT!!!!!!!!!!
September 25, 2016
This is an AMAZING and life-changing product. We had used Zymox for years on one of our German Shepherd's that had chronic ear issues...It was the ONLY thing that worked for him -- after hundreds of later....no permanent resolution. Then, when we were at our wits' end....we discovered Zymox Plus. WIth consistent use -- as directed on the product, our dog's ears have cleared up. We are so very thankful for this product....and will sing its praises to all that will listen. Thank you for offering a natural product that works wonders.
By Wendy
Philadelphia, Pa.
Zymox Plus Otic-HC works
April 27, 2016
I recently realized I've been getting prescription Mometamax for six years with barely a result. My friend recommended I try Zymox Plus so I did. One bottle helped and the second bottle I bought and just started finished the job. For the first time in many years my dog's ear is clean. This product is amazing.
By Fall
California
worth trying
February 8, 2016
Our Springer has had chronic ear problems for a long time and we've tried a lot of things. A couple vets thought we should do surgery (Total Ear Canal Ablasion). I decided to try to manage his symptoms. His left ear is looking very good. His right ear is questionable, but tolerable, I think. We're told he has pseudomonas behind his ear drum. Since this product appears to help control his symptoms, I will be continuing to use it.
By Cathy
Works Great
January 15, 2016
Zymox ear drops helps my dog better than any other product we've tried.
By smoochie
Thank Goodness!
August 11, 2015
After trying several other products coming off the the vet shelf that didn't quite get the job done; this product just works. Real relief for my 13 yr old labradoodle finally.
By Susan
Canyon Lake, Texas
Great product for chronic ear issues
June 3, 2015
I have two Schnauzers, one with grain allergies and she is prone to get ear issues even on grain-free foods. I am so glad I can order this product on line for use when she does get an ear issue. I've been to the vet numerous times and every time, there is no answer, just a big bill and this same product. Now I can safely treat my Nugget's ear issues when they do arise and no additional vet bill! After a week of treatment, her ears are good as new!
By Deb
San Carlos, California
Zymox Enzyme Solution
April 13, 2015
So far so good. My 11 year old Mastif and rott mix dog Titan, keeps getting ear infections, so my vet recommended the solution. :)
By jtmi
Houston, Tx
Works Well
January 20, 2015
This is a great product that works really well. My dogs hate any type of medication, and they don't love getting this one, but it is easy to give to them and works quickly.
By bulldog l.
Cured
January 16, 2015
These drops cured my English bulldog's chronic ear infection. Love it!
By PAGirl
Pittsburgh, PA
so glad i found this
July 15, 2014
Zymox Plus works great, I have a lab with allergies and always getting ear infections, this is so much cheaper than the meds. from the vet and it works overnight she is also always licking her paws making them really red at times. I put this on her paws at night and by morning they are nice and pink again. Even though this doesn't say it is for paws.
By Midgriffith
Middletown, Ohio
Best stuff ever!
June 29, 2014
By day two of usage Simon ear had cleared up the itching had stopped and we were sleeping again. Thank you so much!
By stella
California
this stuff is the best
May 30, 2014
Our dog Stella had constant ear problems! She would shake her head and scratch her ears until they would bleed! They would balloon up and it would be back to the vet. The only solution the vet had was surgery but with no guarantee that it would stop her. We searched for our own solution and came across zymox plus otic enzymatic solution. We bought it hoping it would just give her a little relief. We used it for a week but within the first 2 days it had already dramatically reduced her shaking and swelling! It was amazing! At the end of the week her bad ear looked almost better then her good ear! I don't ordinarily write reviews but my dad said we needed to let everyone whose dog has bad ear problems that there is hope out there. Thank you to the makers of zymox for giving relief from constant ear problems to Stella and us. Hopefully this helps everybody! We will be using this if he ear problems ever return!
By Kat
Love this Product
May 23, 2014
This is the BEST medicine I have ever used on my dogs ears. Poor guy has gone through so many products and trips to the vet to no avail, but this stuff really does work. I would highly recommend it.
By Ricardo
Houston, TX
Awesome!
April 10, 2014
This works exactly as it says it does. My english bulldog had a bit of an ear infection & i used this as directed & it did it's job to perfection. Will definitely be buying some more.
By waterchick60
Zymox HC Soln a 10 out 0f 10.
March 29, 2014
My Labrador had very bad ear infections, After numerous attempts with antibiotics and steroids I asked a friend for advice. She said they used Zymox because it was not an antibiotic but an enzyme formula that "ate" the bacteria. My labs ears have been clear with only a touch up application 1 to 2 times a week.
By ana
Brussels
like magic
March 27, 2014
After suffering for what seems like ages from persistent ear infections and having been treated with several products, this is the one to finally solve the issue for our dog. Very happy!
By Pumpkin's M.
Troy, IL
BEST EVER !!!!!!!
February 9, 2014
I would give this product 25 stars, if I could. My dog has been suffering with itching ears and skin issues for 6 years. She has been on prescription Atopica and a wide range of other products. I had even thought about having her put to sleep because she was soooo miserable. The vets were not able to help much and BELEIVE me we were at their office or on the phone with them many times for these issues. I used this product and saw a difference on the first day. The second day, I did not give the dog any benadryl, the antihistimine I was using to keep her itching under control. I can not say enough good things about this product.I bought the shampoo, the rinse and also the topical cream with the HC. All have been GREAT. I will pass this information on the my vet.
By DRS
SJU PR
THE BEST
November 30, 2013
This is the best product one can find for ear infections.
By YorkieMom
NJ
I think it's a great product, but my dogs hated it
September 24, 2013
Ear scratching, but no smell. Usually use Malecetic Solution, but both my guys have an array of allergies. Figured I try something new. I don't know if the gel-like consistency bothered them, but they both hated it. I continued to use it for the next 3 days, but only by apply it to a q-tip and going into the canal ever so slightly. After they shook their heads, I wiped the product all over the pink of the ears with a cotton ball. It did help them not to scratch, but it was a trial to use. Went back to Malecetic.
By Texas D.
East Texas Piney Woods
Zymox liquid for Dog's ears
July 2, 2013
Our Catahoula suffered with Otitis Externa, constantly scratching her ears. Just one application of Zymox cleared up the itch. She is now a happier dog.
By Ozzie
New Jersey
ZYMOX PLUS Otic HC
June 12, 2013
As usual ZYMOX products are excellent.
I use ZYMOX PLUS Otic HC with my
cocker Spaniels and sometimes with few
clients if need it.
100% quality if you purchase the product.
I use ZYMOX PLUS Otic HC with my
cocker Spaniels and sometimes with few
clients if need it.
100% quality if you purchase the product.
By GC
One Week
June 10, 2013
On and off again frequent ear infections in my pet dog's ears were gone in one week. It is nice to find a product that does what it says it will.
By traif
Boca Raton, FL
great product
May 7, 2013
My poodle, gets ear infections quite regularly, and this helps clear it up
Questions and Answers
 3-PACK Zymox Retail Ear Cleanser (12 oz)Reg price: $46.99Sale price: $38.97 |  6-PACK Zymox Retail Ear Cleanser (24 oz)Reg price: $124.99Sale price: $95.94 |  Zymox Ear Solution w/ Hydrocortisone 0.5% (1.25 oz)Reg price: $29.99Sale price: $22.49 |  Zymox Ear Cleanser (Gallon)Reg price: $120.99Sale price: $92.99 |