Vetoryl
Vetoryl
Vetoryl uses the chemical compound trilostane to treat hyperadrenocortism, or Cushing’s Disease, in dogs. Cortisol is normally produced during times of stress by a variety of enzymes. Trilostane inhibits the enzyme 3-beta-HSD, which produces several hormones used in the synthesis of corticosteroids. By inhibiting the production of these hormones, this enzyme reduces the levels of cortisol that cause the complications associated with hyperadrenocortism.
Of the enzymes that produce corticosteroids, only 3-beta-HSD is not a member of the CYP450 family of enzymes. CYP450 enzymes also produce a variety of other important hormonal steroids such as aldosterone, so trilostane manages to reduce cortisol in an uniquely safe and effective manner. Vetoryl is available in capsules of four different dosages to make it easy to administer the right dosage for your dog.
Key Features:
Uses for Vetoryl Reduces cortisol levels in dogs Treats and alleviates symptoms of Cushing’s Disease (hyperadrenocortism) Use as prescribed by your veterinarian
Please Note: EntirelyPets.com does not carry Vetoryl. The content on this page is for information and education purposes only. Consult with your Veterinarian for more information on Vetoryl.
Conditions For treatment of Cushing’s Disease (hyperadrenocortism) Not for use in puppies or dogs with kidney or liver disease Not for dogs that are nursing or breeding Not for use in dogs with primary hepatic disease or renal insufficiency Please Note: EntirelyPets.com does not carry Vetoryl. The content on this page is for information and education purposes only. Consult with your Veterinarian for more information on Vetoryl.
Dosing Average starting dose is generally 6 mg/kg daily Dosing may be titrated based on individual response Follow the directions of your veterinarian exactly Please Note: EntirelyPets.com does not carry Vetoryl. The content on this page is for information and education purposes only. Consult with your Veterinarian for more information on Vetoryl.
Administration Normally administered once daily with food Starting dose for treatment of Cushing’s Disease in dogs is 1.0-3.0 mg/lb (2.2-6.7 mg/kg) per day Follow your veterinarian’s directions exactly Please Note: EntirelyPets.com does not carry Vetoryl. The content on this page is for information and education purposes only. Consult with your Veterinarian for more information on Vetoryl.
Side Effects The most common reported reactions are inappetence, vomiting, lethargy, diarrhea, and fatigue Morse serious reactions include depression, hemorrhagic diarrhea, collapse, hypoadrenocortical crisis, or adrenal necrosis/rupture- which can be fatal Adverse effects in patients taking Vetoryl are rare (>2%)
Please Note: EntirelyPets.com does not carry Vetoryl. The content on this page is for information and education purposes only. Consult with your Veterinarian for more information on Vetoryl.
Of the enzymes that produce corticosteroids, only 3-beta-HSD is not a member of the CYP450 family of enzymes. CYP450 enzymes also produce a variety of other important hormonal steroids such as aldosterone, so trilostane manages to reduce cortisol in an uniquely safe and effective manner. Vetoryl is available in capsules of four different dosages to make it easy to administer the right dosage for your dog.
Key Features:
Uses for Vetoryl Reduces cortisol levels in dogs Treats and alleviates symptoms of Cushing’s Disease (hyperadrenocortism) Use as prescribed by your veterinarian
Please Note: EntirelyPets.com does not carry Vetoryl. The content on this page is for information and education purposes only. Consult with your Veterinarian for more information on Vetoryl.
Conditions For treatment of Cushing’s Disease (hyperadrenocortism) Not for use in puppies or dogs with kidney or liver disease Not for dogs that are nursing or breeding Not for use in dogs with primary hepatic disease or renal insufficiency Please Note: EntirelyPets.com does not carry Vetoryl. The content on this page is for information and education purposes only. Consult with your Veterinarian for more information on Vetoryl.
Dosing Average starting dose is generally 6 mg/kg daily Dosing may be titrated based on individual response Follow the directions of your veterinarian exactly Please Note: EntirelyPets.com does not carry Vetoryl. The content on this page is for information and education purposes only. Consult with your Veterinarian for more information on Vetoryl.
Administration Normally administered once daily with food Starting dose for treatment of Cushing’s Disease in dogs is 1.0-3.0 mg/lb (2.2-6.7 mg/kg) per day Follow your veterinarian’s directions exactly Please Note: EntirelyPets.com does not carry Vetoryl. The content on this page is for information and education purposes only. Consult with your Veterinarian for more information on Vetoryl.
Side Effects The most common reported reactions are inappetence, vomiting, lethargy, diarrhea, and fatigue Morse serious reactions include depression, hemorrhagic diarrhea, collapse, hypoadrenocortical crisis, or adrenal necrosis/rupture- which can be fatal Adverse effects in patients taking Vetoryl are rare (>2%)
Please Note: EntirelyPets.com does not carry Vetoryl. The content on this page is for information and education purposes only. Consult with your Veterinarian for more information on Vetoryl.